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Results Novel class of anthelmintics To identify new compounds with potential as anthelmintics, we screened a library of 2300 small molecules containing FDA-approved drugs, other known bioactive compounds, and natural products (Spectrum Collection, MicroSource Discovery Systems, Inc.) (Supplementary data 1)

a , Volcano plots showing QC-normalized LC-HRMS/MS feature data and differentially abundant metabolites between WT and gsh2 mutant cells in supernatant (left) and cell extract (right) fractions

29 TyagiP.BanerjeeR.BasuS.YoshimuraN.ChancellorM.HuangL

Therefore, augmenting cardiac ATP production in a bioenergetically efficient manner is of significant interest to the HF field

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