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cup1 and ppr4 epimutants likewise show mitochondrial dysfunction phenotypes and increased efflux, explaining how heterochromatin-island epimutations cause drug resistance

[3] For confirmed deficiency with neurological involvement: 1 mg IM on alternate days until no further improvement, then 1 mg every two months urgent initiation is essential to prevent irreversible nerve damage

Some plant-based foods, such as fortified breakfast cereals, plant-based milk alternatives (e.g., soy milk, almond milk), and nutritional yeast, are fortified with Vitamin B12 (11)

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