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Hansel C, de Jeu M, Belmeguenai A, Houtman SH, Buitendijk GH, Andreev D, et al

Science 250, 10021004

The antimalarial medication quinine has long been used for cramp relief, but after increasing reports of side effects, most severely disseminated intravascular coagulopathy [193], the FDA limited and provided guidelines for the amount of quinine readily available in common formulations [194]