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[5] However, the pathway was fully elucidated only in the 1950s, thanks to the work of several researchers, notably Efraim Racker, Bernard Horecker, Frank Dickens, and Fritz Lipmann, who received the Nobel Prize in Physiology or Medicine in 1953 for his discovery of coenzyme A, not specifically for the pentose phosphate pathway, although his work was highly relevant in the broader context of intermediary metabolism

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10.1136/jnnp.2005.065805

If your dog shows signs of a possible vitamin B12 deficiency, consult your veterinarian for appropriate testing and treatment

Labs use methods like the Paglia and Valentine assay, where samples react with substrates like cumene hydroperoxide, and NADPH consumption is tracked spectrophotometrically