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T-type Calcium Channel Blockade Improves Survival and Cardiovascular Function in Thalassemic Mice

Preclinical Research Summary Preclinical research on BPC-157 has been conducted primarily in animal models designed to investigate tissue repair and regenerative biological processes

[DOI] [Google Scholar] 258.Xu C., Sun L., Ren F., Huang P., Tian Z., Cui J., Zhang W., Wang S., Zhang K., He L., et al

Acknowledgements We thank the staff of the Division of Analytical Science, Hidaka Branch of the Biomedical Research Center, Saitama Medical University, for providing research equipment and offering important advice

Other studies indicate that oxidative stress alone may not always be sufficient to induce apoptosis (or ferroptosis), as alternative antioxidant pathways, such as catalase activity, can compensate for glutathione depletion 34