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Frontiers , Acta Obstetricia et Gynecologica Scandinavica , vol

While the zonation of Wnt expression in endothelial cells is considered to be the basis for the functional zonation of the liver, the differential distribution of -catenin in hepatocytes is related to the expression differences of APC, as APC primarily mediates the degradation of -catenin (Tian et al., 2011)