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The human gallbladder secretes fibroblast growth factor 19 into bile: towards defining the role of fibroblast growth factor 19 in the enterobiliary tract

While computational approaches aimed at predicting such interactions exist, at least in the case of lifespan modulation they remain to be experimentally validated 13

Ter Laak MP, et al

Pisano C, Pratesi G, Laccabue D, Zunino F, Lo Giudice P, Bellucci A, Pacifici L, Camerini B, Vesci L, Castorina M, Cicuzza S, Tredici G, Marmiroli P, Nicolini G, Galbiati S, Calvani M, Carminati P, Cavaletti G

A: It is the first triple agonist (GLP-1 + GIP + Glucagon) studied in Phase 3 trials