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In a mouse model of oral candidiasis, curcumin-PDT significantly reduced fungal load and inflammation, comparable to nystatin treatment (Sakima et al., 2075)

[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Bethea T.N., Wesselink A.K., Weuve J., McClean M.D., Hauser R., Williams P.L., Ye X., Calafat A.M., Baird D.D., Wise L.A

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The activation of RhoA induces myosin-II filament contraction, while simultaneously promoting PTEN activation and suppressing Rac activity, both of which are crucial for the establishment of neutrophil polarization