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Definitions of hypertension, hyperuricemia, dyslipidemia and diabetes According to the Japanese guideline for hypertension 21 , individuals with at least one of the following findings are diagnosed as having hypertension: (1) office blood pressure levels of 140/90 mmHg or more and/or (2) out-of-office blood pressure levels of 135/85 mmHg or more

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Direct CNS Action: Once in the central nervous system (CNS), it exerts localized effects, particularly in regions critical for cognition and memory

Pentoxifylline and berberine mitigate diclofenac-induced acute nephrotoxicity in male rats via modulation of inflammation and oxidative stress