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S1 MS/MS fragments of GS-NEM and GS*-NEM, and p-MRM chromatography of GS-NEM and GS*-NEM co-eluted from HPLC

Frequency Once weekly, subcutaneous

A good part of the human trial evidence is younger and less refined than what we see in animal models, although the trends are similar

14 Adults under 50: ~2.4 mcg per day Adults over 50: 2.4 mcg per day Older adults are advised to supplement with B12 where necessary due to the reduced stomach acid and intrinsic factor and/or medications