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The higher complexity of human thinking and emotions compared to other species, as well as the similarity between non-human primate brains and those of humans in comparison to rodents, necessitate further preclinical studies involving higher animals to validate the alleviating and therapeutic effects of polysaccharides on depression

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After a traumatic impact or jolt to the head, rapid acceleration and deceleration cause the brain to move and bounce around inside the skull

doi: 10.3389/fpubh.2022.996179

3, 4, 5 Traditionally, mast cells and immunoglobulin E (IgE) have long been associated with the pathogenesis of immediate hypersensitivity reaction, the pathophysiologic hallmark of allergic rhinitis, allergic asthma, and anaphylaxis