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Diotallevi et al., Glutathione Fine-Tunes the innate immune response toward antiviral pathways in a macrophage cell line independently of its antioxidant properties, Frontiers in Immunology, vol

Independent studies reported that downregulation of PAEs increased the stiffness of cell walls and impaired the digestibility of pectin to muster effective immune responses against pathogens (Gou et al., 2012