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Randomized phase II trial of encorafenib and cetuximab with or without nivolumab for patients with previously treated, microsatellite stable, BRAFV600E metastatic and/or unresectable colorectal cancer: SWOG S2107

The HPLC flow was coupled to an Agilent 6530 quadrupole time of flight (Q-TOF) mass spectrometer scanning from 70-1000 m/z

Identification of an active site on the laminin alpha5 chain globular domain that binds to CD44 and inhibits malignancy

BRPF1 contains a bromodomain, which is reported to bind H2AK5ac, H4K12ac, and H3K14ac (Poplawski et al, 2014), and two PHD fingers closely linked by a zinc knuckle, which bind to unmodified histone H3 tail and nucleosomal DNA (Klein et al, 2016)