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Treatment of iron deficiency conditions in blood donors: controlled study of iron sulphate versus iron protein succinylate

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The kinetics of the aminoacylation reaction can also be used as a distinctive mechanistic signature, as aminoacyl-tRNA release is the rate limiting step for class I enzymes (except for IleRS and some GluRS) while for class II it is the amino acid activation rate instead (Fersht 1977

Greenwood DC, Thatcher NJ, Ye J, Garrard L, Keogh G, King LG, et al

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