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Les effets secondaires courants incluent, mais ne se limitent pas : douleur ou rougeur au site d'injection diarrhe lgre prurit (dmangeaisons) augmentation du gonflement douleur articulaire vertige mal de tte nervosit ou anxit Les effets secondaires graves peuvent inclure : ractions allergiques thrombose vasculaire priphrique hypokalimie (niveaux bas de potassium) dme pulmonaire (accumulation de liquide autour ou dans les poumons) thrombocytose insuffisance cardiaque congestive Il y a eu des rapports de choc anaphylactique et de dcs aprs l'administration parentrale de vitamine B12

It should be mentioned though that this option was explored only after exhausting relevant over-the-counter options

2011 Jan;96(1):150-8

Additionally, BCL2-inhibitors have been shown to have senolytic effects in some senescent cell models 1,4

A 2025 pilot study published in PubMed confirmed short-term tolerance in 2 participants at 20mg intravenously, though the sample size remains too limited for definitive safety conclusions