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Contents Oral isotretinoin, commonly referred to as Accutane, has become many peoples go-to medication for stubborn acne

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it has a vital role in spermatogenesis and spermatozoon maturation [73,87], it inhibits viral infections (e.g., influenza) [88], it has an important role in the pathogenesis of different diseases such as cancer, inflammation, protein deficiency, Alzheimers disease, Parkinsons disease, hepatic diseases, cystic fibrosis, HIV, heart attacks, hemorrhagic stroke, diabetes, pulmonary disease, gastritis, duodenal ulcer, pancreatic disease, kidney disease, rheumatoid arthritis (RA), autoimmune thyroiditis, muscular dystrophy, amyotrophic lateral sclerosis, preeclampsia, cataract, glaucoma, atherosclerosis, and asthma [37,51,52,73,85,89,90,91,92,93,94,95,96]