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Inflammation (2017) 40:1599605

This response could be caused by an increase in ROS or ammonia, which aged explants cannot process as effectively due to lower GSH production

Indeed, lack of consistent CD-like enteropathy in humanized mice [61] supports the concept that the accelerated disruption of enterocytes secondary to the adaptive CD4 + T cell insult cannot fully explain CD pathogenesis, supporting the notion that an intrinsic defect of the stem cell compartment in subjects at risk of CD is a key element of CD enteropathy [60, 62]

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Sample typeSerum/plasma Detection typeQualitative Certificate: CFDA