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Pioglitazone-loaded PLGA-PEG NPs cross the brain endothelium via endocytosis, improving memory deficits and reducing A deposition in APP/PS1 mice (Silva-Abreu et al., 2018)

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While some studies show discrepancies in results, most report significant differences in OS biomarkers between dogs with MMVD or DCM and healthy controls, suggesting increased oxidative assault and a decline in the efficacy of the antioxidant forces [32,33,34,35,36,37,38,40,41]

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Charlton M, Viker K, Krishnan A, Sanderson S, Veldt B, Kaalsbeek AJ, Kendrick M, Thompson G, Que F, Swain J, Sarr M (2009) Differential expression of lumican and fatty acid binding protein-1: new insights into the histologic spectrum of nonalcoholic fatty liver disease