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196 In the tumor environment, succinate could be produced and released by tumor cells, and via interacting with succinate receptor 1 to activate phosphoinositide-3-kinase/protein kinase B pathway and upregulate HIF-1, inducing macrophage polarization, and enhancing tumor cell metastasis

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Nitric oxide protects intestinal mucosal barrier function and prevents acute graft rejection after intestinal transplantation: a mini-review

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