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About this chapter Cite this chapter Goto, T.K., Yeung, A.W.K., Tanabe, H.C., Ito, Y., Jung, HS., Ninomiya, Y

Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acet amide (PF-06282999): a highly selective mechanism-based myeloperoxidase inhibitor for the treatment of cardiovascular diseases

Methylcobalamin, the active form of B12, demonstrates exceptional activity immediately upon absorption, while other forms such as cyanocobalamin must be converted to methylcobalamin in a twostep process