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A second explanation for the sex bias observed in both COVID-19 and SLE suggests that sex hormones may promote inflammation in women

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At study completion, mice were euthanized via CO2 inhalation (30-70% total chamber volume/min) followed by cervical dislocation and observation of cessation of breathing to confirm mortality

2.1 The Role of Ferroptosis in Atherosclerosis AS is a chronic progressive vascular disease characterized by disturbances in lipid metabolism (Weber and Noels 2011) and narrowing of the arterial lumen through the formation of atherosclerotic plaques in the arterial wall (Veseli et al., 2017