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While GIP has lost most of its insulinotropic activity in patients with T2D, GLP-1 has retained enough of its insulinotropic activity to stimulate insulin secretory responses even in patients with T2D [55]

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(3,9,64) Verschillende preklinische studies wijzen op een neuroprotectieve werking van curcumine bij de ziekte van Parkinson

Furthermore, ACSL4-mediated esterification of PUFAs into peroxidation-vulnerable membrane domains establishes a self-reinforcing pathway, with elevated ACSL4 expression in stroke, AD, and PD intensifying lipid oxidative damage (Zheng et al., 2024), collectively forming an iron-dependent oxidative injury axis