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This is because our body does not get its glutathione from food, but the body has to make its own glutathione every day

Nevertheless, most truncating variants falling within the regulatory domain did behave like null variants suggesting that our assay can still capture some large-effect variants in this domain

FIGURE 4 7 Ferroptosis-based treatment strategies for MM 7.1 Active ingredients of natural products The partial inhibition of cell death by Ferrostatin-1, Liproxstatin-1, or Deferoxamine, alongside evidence that natural product extracts induce MM cell death, implicates ferroptosis in MM cell demise