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The second model demonstrated superior performance, suggesting that integrating features from structures associated with portal hypertension provides a more accurate prediction of mortality in severe AH patients

Lab Monitoring: What Tests You Need and When Standard Isotretinoin Monitoring Protocol The FDA-required iPLEDGE monitoring for isotretinoin includes a fasting lipid panel (triglycerides, total cholesterol, LDL, HDL) at baseline before starting the drug, then at 4 weeks, and then at 4- to 8-week intervals for the duration of treatment [1]

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Statistical analysis The data were analysed with GraphPad Prism 9 software (GraphPad Software, San Diego, CA, USA)