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10.1016/S0021-9258(19)78223-4

Elizabeth N, Natasha J, Matthew G, Kahealani U, Megan S, Karima D, et al

While true pharmacological tolerance to GLP-1 receptor agonists is not well-established, tachyphylaxis of the gastric emptying effect has been documented with GLP-1 receptor agonists

This allows the FTP client program to grab one (usually allocated by the system) and then tell the server to connect using whatever port it happened to grab