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Following high-frequency noise exposure in the auditory cortex, neurons corresponding to the region of hearing loss shift their preferred tuning toward edge frequencies, creating an over-representation of these frequencies in cortical maps

For sections collected in the last well, the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) was processed to detect the potential apoptotic change

HPCAL1 mediates the degradation of CDH2 and reduces plasma membrane tension to promote lipid peroxidation

By driving mTOR-dependent mitochondrial fission, TREM-1 triggers macrophage necroptosis, which in turn aggravates acute lung injury