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Kadia TM, Kantarjian HM, Thomas DA, O'Brien S, Estrov Z, Ravandi F, Jabbour E, Pemmaraju N, Daver N, Wang X, Jain P, Pierce S, Brandt M, Garcia-Manero G, Cortes J, Borthakur G

Neuroinflammation also emerges as a critical determinant: elevated cytokines such as TNF- , IL-1, and IL-6 destabilize synaptic homeostasis, impair inhibitory neurotransmission within descending pain pathways, and exacerbate central sensitization, ultimately limiting the therapeutic impact of tDCS (9698)