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Again, it causes patients to delay treatment or forego it altogether

On the other hand, it has been demonstrated that beclin-1 can not only affect the regulation of autophagy as an autophagy regulator, but also affect the intake of cystine by combining with XCT to form the beclin-1/XCT complex, which leads to the inhibition of GPx4 synthesis and the increase of lipid peroxidation level (41)

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(Gast et al., 1995)

Typically, animal OP models are acute, accompanied by drastic metabolic and hormonal changes, which differ significantly from the natural progression of age-related OP and PMO