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These bioactive constituents work synergistically to exert hypoglycaemic effects, acting through several mechanisms that target key aspects of glucose metabolism and insulin signaling

The broader pattern of GLP-1 drugs reducing addictive and compulsive behavior has shown up across multiple datasets, including a 606,000-veteran cohort published in BMJ earlier this year showing meaningful reductions in alcohol, nicotine, and opioid use disorder rates in GLP-1 users

Amalesh Nanda et al (75)

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Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial