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Personalized Genome-Scale Modeling Reveals Metabolic Perturbations in Fibroblasts of Methylmalonic Aciduria Patients

Behavior experiments Animals were excluded from statistical analysis if data collection failed due to technical errors (e.g., equipment malfunction, improper sample handling, or missed experimental procedures)

However, the causes of B12 deficiency in other population groups must be sought in other contexts, as they do consume this vitamin regularly through their diet, but something is wrong (they do not absorb it well, they do not have the necessary binding proteins, they have a pathology or infection that affects it, they do not produce enough hydrochloric acid, etc.)