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Intermediate products of intracellular fatty acid metabolism, like long-chain fatty acyl-CoA (LCFA-CoA) molecules, constitute a signal of satiety occurring when free fatty acids are in abundance

During this process, they directly damage mitochondrial structures and alter metabolic pathways

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What is also unknown is the effect on cognition, and any neuroprotective benefit, in younger or healthy individuals remains unknown, some positive results have been reported, 6 however a large scale confirmatory study is still required