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However, during Phase 1 there was one report of a mild adverse reaction (lethargy, decreased appetite), and that family chose not to continue to Phase 2

10.1016/S1532-0456(00)00192-7

Then, it is coupled with traditional viral or non-viral vectors through the surface groups of the magnetic particles, and then combined with the target gene to form gene-loaded magnetic microspheres

J Zhejiang Univ Sci B (2010) 11(2):13643