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An experimental model of Stanford type B aortic dissection

In terms of therapeutic translation, ERS-targeting strategies can be broadly categorized into two approaches: first, direct modulation of core ERS molecules, such as combining the PERK agonist CCT020312 with taxanes to overcome drug resistance [105, 106]

70 Intrahepatic metabolic regulation and immune homeostasis by SCFAs SCFAs produced by gut microbial fermentation of dietary fiber, mainly including acetate, propionate, and butyrate, are key metabolic messengers connecting gut flora and liver health

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