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Tan D, Reiter RJ

This actin-buffering capacity is critical for dynamic cellular processes including: Cell migration: Rapid actin polymerization at the leading edge Morphological changes: Cytoskeletal reorganization Intracellular transport: Actin filament dynamics The peptide contains a conserved LKKTETQ actin-binding motif that is essential for its interaction with G-actin

Figure 1 The C- and N-termini constitute the cytoplasmic region of TRPs (Huffer et al., 2020)

Among the genes implicated, MECP2 stands out, given its association with Rett syndrome, a condition with clinical features overlapping with ASD

Wang X, Wu R, Zhai P, Liu Z, Xia R, Zhang Z, et al