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[,,] In rat models of cirrhotic PH or non-cirrhotic PH, splenectomy ameliorates portal pressure and systemic hemodynamics (as indicated by a lower heart rate and higher mean arterial pressure), however, hypersplenism related anemia and thrombocytopenia are only significantly improved in non-cirrhotic PH rat model

During data processing, the unique adverse event report identifier (PRIMARYID) was used to link drug-specific PRIMARYID lists with the main database

doi: 10.1016/j.mito.2014.03.012 45

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Cell lines were cryopreserved at early passage, regularly Mycoplasma tested and used within 20 passages