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Chronic B12 deficiency can contribute to elevated inflammatory markers, potentially increasing cardiovascular disease risk and other inflammatory conditions

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Molecular Characteristics Peptide Sequence: Ala-Glu-Asp-Gly (AEDG) Molecular Formula: CHNO Molecular Weight: 390.349 g/mol PubChem CID: 219042 CAS Number: 307297-39-8 Mechanisms of Action and Pathways Studied 1

Patients with new-onset symptoms showed higher rehabilitation program participation compared to those without symptoms (64.3% vs 48.3%, p = 0.001), despite similar stroke severity (mRS: median 2 [IQR 1-3] vs 2 [1-3], p = 0.137

Furthermore, ligands derived from the hexapeptide Ang IV but that are not proven to act as IRAP inhibitors have been reported