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Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)

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doi: 10.3389/fpls.2019.01089 Received 31 August 2018 Accepted 09 August 2019 Published 13 September 2019 Volume 10 - 2019 Edited by Michael James Considine, University of Western Australia, Australia Reviewed by Sophie Hendrix, University of Hasselt, Belgium

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