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[DOI] [PubMed] [Google Scholar] 7.Bewick GA, Gardiner JV, Dhillo WS, Kent AS, White NE, Webster Z, Ghatei MA, Bloom SR

The replacement of His(4) in angiotensin IV by conformationally constrained residues provides highly potent and selective analogues

If adding amylin agonism to a single GLP-1 agonist (CagriSema) produces 20.4% weight loss, the theoretical potential of adding it to a triple agonist is significant