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Non-hospital costs : These include physician services costs obtained from the Ontario Schedule of Physician Benefits, laboratory fees from the Ontario Schedule of Laboratory Fees, drug costs from the Ontario Drug Benefit Formulary, and device costs from the perspective of local health care institutions whenever possible, or from the device manufacturer

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Solvent A: 0.10% formic acid in water, Solvent B: 0.00% formic acid in acetonitrile