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Furthermore, citrate is an intermediate for sterol and fatty acid biosynthesis 614,615 and is used in astrocytes for the production of cholesterol, supporting synaptogenesis 616 , lipogenesis and lipid droplet formation in astrocytes 614,615

The DEGs were selected on the basis of statistical significance ( p 0.05), annotated, and mapped to biological pathways in the Kyoto Encyclopedia of Genes and Genomes (KEGG) database 19