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The lactate signaling pathway primarily targets ATP-sensitive potassium (K-ATP) channels to regulate neuronal firing, with these channels being a key target for lactate signaling (Karagiannis et al., 2021)

In terms of stress responses, AtGSTL1 is strongly up-regulated in several conditions including biotic interactions, treatment with chemicals, salt and iron-starvation stresses and, to a lesser extent, in response to hypoxia