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This oral activity is attributed to the lipophilic amino acid stretch within the C-terminal fragment

In this setting, CD38 is expressed on several immunosuppressive cell types including regulatory T cells (Tregs), regulatory B cells (Bregs), myeloid-derived suppressor cells (MDSCs), and NK cell subsets [42]

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At a follow-up appointment approximately 3 months after symptom onset, JCs bilateral lower extremity strength had improved