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These advancements have progressively improved patient outcomes, with current frontline combination therapies extending median overall survival beyond 30 months in clinical trials [13, 14]

HbS polymers rapidly elongate to form fibrous strands, inducing erythrocyte sickling [12]

She obtained her Masters Degree from New York University, and since then has practiced in the Emergency Department at Montefiore Medical Center in the Bronx, NY, as well as Internal Medicine and Primary Care in Jamaica, NY