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Kruskal-Wallis test was used to evaluate the associations between ANALI score and continuous biomarker levels while Pearsons Chi-square test for the categorical parameters, including IBD status and cholangitis event

The search databases were selected for their different but complementary capabilities

Site burden compounds this: as trials expand globally, particularly into Asia-Pacific and other emerging markets, sites increasingly switch between different sponsor-specific systems and processes, which industry commentary describes as a central operational risk in 2026 rather than a solved problem

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