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1 In many cases, primary CRC can be treated with surgery, chemotherapy and radiotherapy

Furthermore, NO can modulate iron homeostasis by promoting the release of iron from ferritin, which increases the labile iron pool (Fe 2+ ) available to catalyze the Fenton reaction and amplify lipid peroxidation

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Y., Lee S.-P., Denney D

Multifaceted roles of glutathione and glutathione-based systems in carcinogenesis and anticancer drug resistance