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Dhar et al

This paradigm shift in peptide engineering combines data-driven insights with traditional rational design principles, substantially expanding the landscape of feasible peptide therapeutics

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In transverse aortic constriction (TAC) model rats, TSA markedly reduced malondialdehyde (MDA) levels in myocardial tissue and decreased pro-inflammatory cytokine levels (TNF- and IL-6), while increasing superoxide dismutase (SOD) activity, ultimately attenuating pressure overload-induced cardiac remodeling (45)