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It aims to synthesize findings from preclinical and clinical studies regarding the efficacy of synbiotics in improving cognitive function and AD pathology, elucidate the underlying biological mechanisms including GM modulation, SCFA production, immune regulation, and gut-brain signaling, and identify key challenges and future research directions for translating GM-targeted interventions into effective AD therapies

We need to understand that this issue does not affect each individual

These results demonstrate that GSTA1 expression is negatively associated with the accumulation of LD and might be a protective factor for the progression of MASLD

Characterization of therapeutic protein will also require rigor but more emphases will be placed on biochemical, immunological and functional testing

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