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They can be secondary to a reduced MTHFR activity ( 38 mol/L, according to Graham et al, 1997)

Loss of SLC7A11 results in lysosomal hyperacidity and labile iron release, sensitizing cells to ferroptosis

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ATP7A and ATP7B are triggered when intracellular copper levels become too high [60]

Listen to your recovery metrics and dial back intensity if you're feeling constantly drained