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& Breteler, M

Since GGT plays a significant role in cancer cells to produce GSH to relieve oxidative stress, inhibiting the GGT activity would lead to elevated ROS levels 39

In this regard, it is interesting that NLRP3-independent inflammasome stimuli, such as the AIM2 ligand poly(dA:dT) and the NLRC4 activator flagellin, have also been reported to increase levels of ubiquitylated IL-1 49