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For example, studies using Drosophila models with mutations in genes such as TBC1D24 and KCNA1 have shown how different genetic backgrounds can alter the efficacy of drugs such as antioxidants or channel modulators

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FIGURE 7 In summary, the antioxidant stress of GPX8 is not only related to the oxidative folding of endoplasmic reticulum proteins, but also may play a vital role in regulating endoplasmic reticulum Ca 2+

We analyzed data from the Phase 3 D-LIVR study to characterize HDV and HBsAg kinetics in patients treated with pegIFN and LNF

doi:10.1016/s0149-2918(03)90011-7 Sindrup SH, Otto M, Finnerup NB, Jensen TS